Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | IDH2 | P48735 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23360460 | 1.00 | GPR119 (0.51) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL28834065 | 0.94 | USP30 (0.49) | GPR119PIM1PIM2CNR1PARP1 | |
| SCHEMBL28834064 | 0.94 | USP30 (0.49) | GPR119PIM1PIM2CNR1PARP1 | |
| SCHEMBL29933464 | 0.94 | USP30 (0.49) | GPR119PIM1PIM2CNR1PARP1 | |
| SCHEMBL23359875 | 0.92 | GPR119 (0.51) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL23360477 | 0.89 | ALDH1A1 (0.47) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL29862739 | 0.89 | ALDH1A1 (0.47) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL23360170 | 0.89 | ALDH1A1 (0.49) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL29862457 | 0.89 | ALDH1A1 (0.49) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL23360517 | 0.88 | ALDH1A1 (0.50) | GPR119ALDH1A1NPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |