Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | PDE1A | P54750 | 2/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24540240 | 0.77 | TDP1 (0.42) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21078678 | 0.77 | ADORA2A (0.46) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24075522 | 0.74 | HDAC1 (0.39) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23120978 | 0.73 | CNR2 (0.33) | SLC29A1FGFR1FGFR4 | |
| SCHEMBL23120979 | 0.73 | CNR2 (0.33) | SLC29A1FGFR1FGFR4 | |
| SCHEMBL24075549 | 0.72 | SLC29A1 (0.37) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24075523 | 0.71 | DOT1L (0.35) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12379187 | 0.71 | YTHDC1 (0.54) | SLC29A1YTHDC1 | |
| SCHEMBL24075634 | 0.71 | DOT1L (0.37) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28948817 | 0.71 | SLC29A1 (0.35) | SLC29A1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013756-A1 | MLL1 INHIBITORS AND ANTI-CANCER AGENTS | Novartis AG (CH) | 2022-06-22 | — | — | EP | disclosed |