Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | PMM2 | O15305 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYBB | P04839 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615461 | 0.87 | METAP2 (0.57) | METAP2MAPTKDM4EMEN1QSOX1 | |
| SCHEMBL5916623 | 0.76 | METAP2 (0.61) | METAP2MAPTKDM4EMEN1QSOX1 | |
| SCHEMBL29864741 | 0.74 | MPI (0.44) | MAPTKDM4EMEN1PMM2ALDH1A1 | |
| SCHEMBL30573263 | 0.73 | METAP2 (0.51) | METAP2MAPTKDM4EMEN1QSOX1 | |
| SCHEMBL5916901 | 0.73 | METAP2 (0.54) | METAP2MAPTKDM4EMEN1QSOX1 | |
| SCHEMBL10958968 | 0.73 | METAP2 (0.51) | METAP2MAPTKDM4EMEN1QSOX1 | |
| SCHEMBL5916583 | 0.70 | METAP2 (0.54) | METAP2MAPTKDM4EMEN1QSOX1 | |
| SCHEMBL5916849 | 0.69 | LMNA (0.48) | METAP2MAPTKDM4EMEN1QSOX1 | |
| SCHEMBL5916782 | 0.69 | METAP2 (0.61) | METAP2MAPTKDM4EMEN1QSOX1 | |
| SCHEMBL10956173 | 0.69 | METAP2 (0.53) | METAP2MAPTKDM4EMEN1QSOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200978-B | Isothia (selenium) azolone derivative and application thereof in anti-coronavirus drugs | 中国海洋大学 | 2022-09-16 | — | — | CN | disclosed |