Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL781713 | 1.00 | PABPC1 (0.47) | PABPC1BACE1HTTMMP2MMP9 | |
| SCHEMBL25074945 | 0.86 | PABPC1 (0.47) | PABPC1BACE1HTTMMP2MMP9 | |
| SCHEMBL31097091 | 0.86 | PABPC1 (0.47) | PABPC1BACE1HTTMMP2MMP9 | |
| SCHEMBL31097094 | 0.86 | PABPC1 (0.47) | PABPC1BACE1HTTMMP2MMP9 | |
| SCHEMBL781743 | 0.79 | PIK3CG (0.47) | BACE1ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL780542 | 0.79 | HTT (0.44) | PABPC1BACE1HTTMMP2MMP9 | |
| SCHEMBL6677171 | 0.79 | BACE1 (0.41) | BACE1ADORA2AALDH1A1KDM4EMEN1 | |
| SCHEMBL13927902 | 0.79 | — | — | |
| SCHEMBL5461503 | 0.79 | NCK1 (0.41) | BACE1ADORA2AALDH1A1KDM4EMEN1 | |
| SCHEMBL25074844 | 0.79 | ALDH1A1 (0.36) | PABPC1BACE1HTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901646-B | Benzotriazine bisoxides and pharmaceutical compositions thereof | 浙江瑞臻医药有限公司 | 2024-06-04 | — | — | CN | disclosed |
| WO-2023019912-A9 | BENZOTRIAZINE DIOXIDE AND PHARMACEUTICAL COMPOSITION THEREOF | 杭州瑞臻医药有限公司 | 2023-06-01 | — | — | WO | disclosed |
| WO-2023019912-A1 | BENZOTRIAZINE DIOXIDE AND PHARMACEUTICAL COMPOSITION THEREOF | 杭州瑞臻医药有限公司 | 2023-02-23 | — | — | WO | disclosed |
| CN-114901646-A | Benzotriazine double oxide and pharmaceutical composition thereof | 杭州瑞臻医药有限公司 | 2022-08-12 | — | — | CN | disclosed |