Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PRNP | P04156 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25074786 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL25074716 | 0.93 | IDO1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL29864668 | 0.93 | IDO1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL25242671 | 0.87 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL29864669 | 0.86 | CRHBP (0.39) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL25074939 | 0.86 | CRHBP (0.39) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL29864680 | 0.85 | HTT (0.35) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL25074843 | 0.85 | HTT (0.35) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL25218098 | 0.85 | HTT (0.35) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL29864598 | 0.85 | HTT (0.35) | ALDH1A1HPGDKDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901646-B | Benzotriazine bisoxides and pharmaceutical compositions thereof | 浙江瑞臻医药有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-114901646-A | Benzotriazine double oxide and pharmaceutical composition thereof | 杭州瑞臻医药有限公司 | 2022-08-12 | — | — | CN | disclosed |