Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 9/20 | 0.50 |
| ▸ | MDM4 | O15151 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31166669 | 1.00 | CASP1 (0.50) | CASP1MDM4TP53CASP3TNF | |
| SCHEMBL29398340 | 0.96 | CASP3 (0.53) | CASP1MDM4TP53CASP3TNF | |
| SCHEMBL30641530 | 0.96 | CASP3 (0.53) | CASP1MDM4TP53CASP3TNF | |
| SCHEMBL119369 | 0.96 | CASP3 (0.53) | CASP1MDM4TP53CASP3TNF | |
| SCHEMBL29400275 | 0.96 | CASP3 (0.53) | CASP1MDM4TP53CASP3TNF | |
| SCHEMBL30826385 | 0.96 | CASP3 (0.53) | CASP1MDM4TP53CASP3TNF | |
| SCHEMBL10187049 | 0.96 | CASP3 (0.53) | CASP1MDM4TP53CASP3TNF | |
| SCHEMBL8037759 | 0.96 | CASP3 (0.53) | CASP1MDM4TP53CASP3TNF | |
| SCHEMBL30802532 | 0.96 | CASP3 (0.53) | CASP1MDM4TP53CASP3TNF | |
| SCHEMBL30656568 | 0.90 | MDM4 (0.59) | MDM4TP53CASP3TNFMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115057910-A | Complement activity regulator, preparation method and medical application thereof | 上海翰森生物医药科技有限公司 | 2022-09-16 | — | — | CN | disclosed |