Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.40 |
| ▸ | ITGAL | P20701 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16974763 | 0.81 | NOTUM (0.39) | NOTUMKCNMA1F11KLKB1 | |
| SCHEMBL29804049 | 0.80 | NOTUM (0.42) | NOTUMKCNMA1F11KLKB1 | |
| SCHEMBL16974775 | 0.80 | NOTUM (0.42) | NOTUMKCNMA1F11KLKB1 | |
| SCHEMBL1196285 | 0.80 | GABRA2 (0.45) | KCNMA1CA2CA9LMNA | |
| SCHEMBL1196287 | 0.80 | GABRA2 (0.45) | KCNMA1CA2CA9LMNA | |
| SCHEMBL617053 | 0.79 | NOTUM (0.44) | NOTUMITGB2ICAM1ITGALTBXA2R | |
| SCHEMBL30194022 | 0.79 | F11 (0.53) | F11KLKB1 | |
| SCHEMBL478536 | 0.79 | F11 (0.53) | F11KLKB1 | |
| SCHEMBL478538 | 0.79 | F11 (0.53) | F11KLKB1 | |
| SCHEMBL617054 | 0.79 | NOTUM (0.44) | NOTUMITGB2ICAM1ITGALTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115066417-B | Factor XIa inhibitors | 上海京新生物医药有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-115066417-A | Factor XIa inhibitors | 上海京新生物医药有限公司 | 2022-09-16 | — | — | CN | disclosed |