⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29866374 | 0.86 | TYK2 (0.32) | — | |
| SCHEMBL25573075 | 0.86 | TYK2 (0.32) | — | |
| SCHEMBL29866212 | 0.83 | RXFP1 (0.30) | — | |
| SCHEMBL29866286 | 0.81 | TYK2 (0.40) | — | |
| SCHEMBL29866515 | 0.79 | MAPT (0.31) | — | |
| SCHEMBL29766676 | 0.77 | DRD4 (0.38) | — | |
| SCHEMBL30696907 | 0.71 | — | — | |
| SCHEMBL29865749 | 0.71 | CSNK1D (0.33) | — | |
| SCHEMBL29866438 | 0.70 | TYK2 (0.44) | — | |
| SCHEMBL25573092 | 0.70 | TYK2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532485-A1 | TYK2 INHIBITORS AND USES THEREOF | Sudo Biosciences Limited (GB) | 2025-04-09 | — | — | EP | disclosed |
| CN-117242072-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2023227946-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2023-11-30 | — | — | WO | disclosed |
| WO-2022175747-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-08-25 | — | — | WO | disclosed |