Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | LPL | P06858 | 2/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.37 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27087930 | 1.00 | ALDH1A1 (0.39) | ALDH1A1HIF1ALPLLIPGESPL1 | |
| SCHEMBL23830122 | 0.87 | ALDH1A1 (0.40) | ALDH1A1HIF1ALPLLIPGESPL1 | |
| SCHEMBL59736 | 0.81 | ATM (0.49) | ALDH1A1HIF1ALPLLIPGESPL1 | |
| SCHEMBL2489484 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HIF1ALPLLIPGESPL1 | |
| SCHEMBL26153570 | 0.81 | LPL (0.48) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL18681344 | 0.78 | LPL (0.36) | ALDH1A1HIF1ALPLLIPGESPL1 | |
| SCHEMBL30140094 | 0.78 | LPL (0.36) | ALDH1A1HIF1ALPLLIPGESPL1 | |
| SCHEMBL15440424 | 0.77 | KMT2A (0.44) | ALDH1A1HIF1ACYP1A2GPR35TDP1 | |
| SCHEMBL15979556 | 0.77 | ALDH1A1 (0.36) | ALDH1A1HIF1ALPLLIPGESPL1 | |
| SCHEMBL156963 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP1A2GPR35TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320103-A1 | PYRIMIDINE BASED RAS MODULATORS AND USES THEREOF | Quanta Therapeutics, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022217118-A1 | PYRIMIDINE BASED RAS MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2022-10-13 | — | — | WO | disclosed |