Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | PNMT | P11086 | 5/20 | 0.48 |
| ▸ | CD44 | P16070 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120623 | 1.00 | ASIC3 (0.55) | ASIC3PLAUDRD2DRD3PNMT | |
| Hydrochloric Acid SCHEMBL4789548 | 0.98 | ASIC3 (0.53) | ASIC3PLAUDRD2DRD3PNMT | |
| SCHEMBL3240122 | 0.93 | PNMT (0.55) | DRD2DRD3PNMTCD44MAOB | |
| Hydrochloric Acid SCHEMBL22465809 | 0.91 | PNMT (0.53) | DRD2DRD3PNMTCD44MAOB | |
| SCHEMBL18766202 | 0.89 | HTR2C (0.52) | PLAUDRD2DRD3ADRA2AADRA2B | |
| SCHEMBL1206291 | 0.84 | HTR2A (0.40) | PLAUDRD2DRD3PNMTADRA2A | |
| SCHEMBL31514914 | 0.84 | HTR2A (0.40) | PLAUDRD2DRD3PNMTADRA2A | |
| Hydrochloric Acid SCHEMBL3710885 | 0.82 | HTR2A (0.39) | PLAUDRD2DRD3PNMTADRA2A | |
| SCHEMBL1696305 | 0.81 | ASIC3 (0.55) | ASIC3PLAUDRD2DRD3PNMT | |
| SCHEMBL22542122 | 0.81 | ASIC3 (0.55) | ASIC3PLAUDRD2DRD3PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320101-A2 | SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS | Revolution Medicines, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| CN-117412954-A | Synthesis of rapamycin analog compounds | 锐新医药公司 | 2024-01-16 | — | — | CN | disclosed |
| WO-2022216900-A2 | SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS | Revolution Medicines, Inc. (US) | 2022-10-13 | — | — | WO | disclosed |