Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563246 | 1.00 | KMT2A (0.71) | KMT2AMAPTSMN1; SMN2TSHRTDP1 | |
| SCHEMBL13056646 | 0.91 | KMT2A (0.61) | KMT2AMAPTSMN1; SMN2TSHRTDP1 | |
| SCHEMBL21531127 | 0.90 | KMT2A (0.60) | KMT2AMAPTSMN1; SMN2TSHRTDP1 | |
| SCHEMBL13248198 | 0.86 | KMT2A (0.56) | KMT2AMAPTSMN1; SMN2TSHRTDP1 | |
| SCHEMBL13248200 | 0.86 | MAPT (0.58) | KMT2AMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30670380 | 0.86 | MAPT (0.58) | KMT2AMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL563763 | 0.86 | PKM (0.67) | KMT2AMAPTSMN1; SMN2TSHRTDP1 | |
| SCHEMBL23705193 | 0.85 | KMT2A (0.55) | KMT2AMAPTSMN1; SMN2TSHRTDP1 | |
| SCHEMBL21973136 | 0.85 | MAPT (0.57) | KMT2AMAPTSMN1; SMN2TDP1KDM4E | |
| SCHEMBL21113593 | 0.85 | KMT2A (0.55) | KMT2AMAPTSMN1; SMN2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115066438-A | ASGPR binding compounds for degrading extracellular proteins | 阿维拉治疗公司 | 2022-09-16 | — | — | CN | disclosed |