Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233037 | 0.91 | ALDH1A1 (0.67) | PKMKMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL8107611 | 0.90 | MAPT (0.60) | PKMKMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL14364287 | 0.88 | MAPT (0.60) | PKMKMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL29390514 | 0.87 | KMT2A (0.70) | PKMKMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL8147273 | 0.87 | MAPT (0.65) | PKMKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL126989 | 0.87 | KMT2A (0.70) | PKMKMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL563246 | 0.86 | KMT2A (0.71) | PKMKMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL29868082 | 0.86 | KMT2A (0.71) | PKMKMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL27562350 | 0.84 | KMT2A (0.52) | PKMKMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL8053888 | 0.84 | ALDH1A1 (0.63) | PKMKMT2AALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124552-A4 | ANTITUMOR CHRYSENE DERIVATIVES | REGENTS BOARD OF (US) | 2005-01-05 | — | — | EP | claimed |
| EP-1124552-A1 | ANTITUMOR CHRYSENE DERIVATIVES | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2001-08-22 | — | — | EP | claimed |
| WO-2000024394-A1 | ANTITUMOR CHRYSENE DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-05-04 | — | — | WO | claimed |
| US-12084517-B2 | Chimeric small molecules for the recruitment of antibodies to cancer cells | YALE UNIVERSITY (US) | 2024-09-10 | — | — | US | disclosed |
| US-20240067756-A1 | CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS | UNIV YALE (US) | 2024-02-29 | — | — | US | disclosed |
| US-20240067756-A1 | CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS | UNIV YALE (US) | 2024-02-29 | — | — | US | disclosed |
| US-11725064-B2 | Chimeric small molecules for the recruitment of antibodies to cancer cells | YALE UNIVERSITY (US) | 2023-08-15 | — | — | US | disclosed |
| US-11725064-B2 | Chimeric small molecules for the recruitment of antibodies to cancer cells | YALE UNIVERSITY (US) | 2023-08-15 | — | — | US | disclosed |
| US-20220023428-A1 | CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-01-27 | — | — | US | disclosed |
| US-11014992-B2 | Chimeric small molecules for the recruitment of antibodies to cancer cells | YALE UNIVERSITY (US) | 2021-05-25 | — | — | US | disclosed |
| US-20200354476-A1 | CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS | UNIV YALE (US) | 2020-11-12 | — | — | US | disclosed |
| EP-1684816-A2 | METHODS OF PREPARING CROSSLINKED MATERIALS AND BIOPROSTHETIC DEVICES | Medtronic, Inc. (US) | 2006-08-02 | — | — | EP | disclosed |
| US-7053051-B2 | Methods of preparing crosslinked materials and bioprosthetic devices | MEDTRONIC, INC. (US) | 2006-05-30 | — | — | US | disclosed |
| US-20050136510-A1 | Methods of preparing crosslinked materials and bioprosthetic devices | MEDTRONIC, INC. | 2005-06-23 | — | — | US | disclosed |
| WO-2005042043-A2 | METHODS OF PREPARING CROSSLINKED MATERIALS AND BIOPROSTHETIC DEVICES | MEDTRONIC, INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| EP-1285269-B1 | LIPID UPTAKE ASSAYS | DEVGEN NV (BE) | 2005-02-02 | — | — | EP | disclosed |
| US-6703214-B2 | MICROSCOPIC NEMATODES IN FUNCTIONAL HIGH THROUGHPUT IN VIVO ASSAYS FOR DETECTION OF INHIBITORS OR ACTIVATORS OF INTESTINAL LIPID UPTAKE | DEVGEN NV (BE) | 2004-03-09 | — | — | US | disclosed |
| EP-1285269-A2 | LIPID UPTAKE ASSAYS | Devgen NV (BE) | 2003-02-26 | — | — | EP | disclosed |
| US-20020137205-A1 | Lipid uptake assays | DEVGEN N.V. (BE) | 2002-09-26 | — | — | US | disclosed |
| WO-2001088533-A2 | LIPID UPTAKE ASSAYS | DEVGEN NV (BE) | 2001-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725064-B2 | Chimeric small molecules for the recruitment of antibodies to cancer cells | BRDT, PAICS, KLK3 | PKM 4075/4885KMT2A 606/4885ALDH1A1 2479/4885 |
| US-20220023428-A1 | CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS | BRDT, PAICS, KLK3 | PKM 4075/4885KMT2A 606/4885ALDH1A1 2479/4885 |
| US-20200354476-A1 | CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS | BRDT, PAICS, KLK3 | PKM 4075/4885KMT2A 606/4885ALDH1A1 2479/4885 |
| US-20240067756-A1 | CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS | BRDT, PAICS, KLK3 | PKM 4075/4885KMT2A 606/4885ALDH1A1 2479/4885 |
| US-11014992-B2 | Chimeric small molecules for the recruitment of antibodies to cancer cells | BRDT, PAICS, KLK3 | PKM 4075/4885KMT2A 606/4885ALDH1A1 2479/4885 |
| US-12084517-B2 | Chimeric small molecules for the recruitment of antibodies to cancer cells | BRDT, PAICS, KLK3 | PKM 4075/4885KMT2A 606/4885ALDH1A1 2479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.