SCHEMBL298682

SCHEMBL298682

Oc1cccc(CNCCN(CCNCc2cccc(O)c2O)CCNCc2cccc(O)c2O)c1O

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.53
CA2 P00918 5/20 0.53
CA9 Q16790 4/20 0.50
TSHR P16473 2/20 0.50
KDM4E B2RXH2 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MPO P05164 9/20 0.49
CYP2D6 P10635 1/20 0.47
HIF1A Q16665 1/20 0.47
SLC6A4 P31645 2/20 0.46
TERT O14746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8939973 0.85 CA12 (0.74) CA12CA2CA9TSHRKDM4E
Hydrochloric Acid SCHEMBL8940039 0.84 CA12 (0.71) CA12CA2CA9TSHRKDM4E
SCHEMBL12765730 0.82 TSHR (0.67) CA12CA2CA9TSHRKDM4E
SCHEMBL22551107 0.80 CA12 (0.56) CA12CA2CA9TSHRKDM4E
SCHEMBL15483816 0.77 CA12 (0.67) CA12CA2CA9TSHRKDM4E
SCHEMBL13973324 0.77 TSHR (0.54) CA12CA2CA9TSHRKDM4E
SCHEMBL17714018 0.73 MPO (0.64) CA12CA2CA9TSHRKDM4E
SCHEMBL29761161 0.73 MPO (0.64) CA12CA2CA9TSHRKDM4E
SCHEMBL8940036 0.73 MPO (0.65) CA12CA2CA9TSHRKDM4E
SCHEMBL13186842 0.71 EGFR (0.51) CA12CA2CA9TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3724168-B1 NEW DAZA CHELATORS AS LIGANDS IN LIVER IMAGING X NUCLEAR DIAGNOSTICS GMBH (DE) 2025-07-30 EP disclosed
US-11701439-B2 DAZA chelators as ligands in liver imaging X-NUCLEAR DIAGNOSTICS GMBH (DE) 2023-07-18 US disclosed
US-20210069357-A1 NEW DAZA CHELATORS AS LIGANDS IN LIVER IMAGING Universitätsklinikum Jena (DE) 2021-03-11 US disclosed
EP-3724168-A1 NEW DAZA CHELATORS AS LIGANDS IN LIVER IMAGING Universitätsklinikum Jena (DE) 2020-10-21 EP disclosed
CN-111630037-A Novel DAZA chelators as ligands in liver imaging 耶拿大学综合医院 2020-09-04 CN disclosed
WO-2019115429-A1 NEW DAZA CHELATORS AS LIGANDS IN LIVER IMAGING Universitätsklinikum Jena (DE) 2019-06-20 WO disclosed
US-8912332-B2 Synthesis of trivalent flexible frameworks with ligands comprising catechol units for functionalizing surfaces JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) 2014-12-16 US disclosed
EP-2428503-B1 Synthesis of tripodal catechol derivatives with a flexible base for functionalising surfaces Justus Liebig Universität Giessen (DE) 2014-12-10 EP disclosed
US-20130245270-A1 Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) 2013-09-19 US disclosed
WO-2012032085-A1 SYNTHESIS OF TRIVALENT FLEXIBLE FRAMEWORKS WITH LIGANDS COMPRISING CATECHOL UNITS FOR FUNCTIONALIZING SURFACES JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) 2012-03-15 WO disclosed
EP-2428503-A1 Synthesis of tripodal catechol derivatives with a flexible base for functionalising surfaces Justus-Liebig-Universität Gießen (DE) 2012-03-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130245270-A1 Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces CHRM3, CHRM5, CHRM4 CA12 532/4885CA2 1639/4885CA9 830/4885
US-20210069357-A1 NEW DAZA CHELATORS AS LIGANDS IN LIVER IMAGING DAZAP1, SLC39A11, SLC10A1 CA12 5/4885CA2 161/4885CA9 19/4885
US-11701439-B2 DAZA chelators as ligands in liver imaging DAZAP1, SLC39A11, SLC10A1 CA12 5/4885CA2 178/4885CA9 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.