Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 12/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10526958 | 0.88 | MPO (0.80) | MPOSLC6A4CA12CA2TSHR | |
| SCHEMBL8939973 | 0.83 | CA12 (0.74) | MPOSLC6A4CA12CA2TSHR | |
| Hydrochloric Acid SCHEMBL8940039 | 0.81 | CA12 (0.71) | MPOSLC6A4CA12CA2TSHR | |
| SCHEMBL4135922 | 0.81 | MPO (0.69) | MPOSLC6A4CA12CA2TSHR | |
| Hydrochloric Acid SCHEMBL10962861 | 0.79 | MPO (0.67) | MPOSLC6A4CA12CA2TSHR | |
| SCHEMBL10960531 | 0.79 | HTR1A (0.50) | MPOHTR1ASLC6A4CA12CA2 | |
| SCHEMBL25454282 | 0.77 | MPO (0.69) | MPOHTR1ASLC6A4CA12CA2 | |
| SCHEMBL10965036 | 0.76 | MPO (0.62) | MPOHTR1ASLC6A4CA12CA2 | |
| Hydrochloric Acid SCHEMBL3883322 | 0.76 | MPO (0.67) | MPOHTR1ASLC6A4CA12CA2 | |
| SCHEMBL15483816 | 0.75 | CA12 (0.67) | MPOSLC6A4CA12CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711180-A4 | FUNCTIONALIZED TRIPODAL LIGANDS FOR IMAGING APPLICATIONS | MALLINCKRODT MEDICAL INC (US) | 1996-11-27 | — | — | EP | disclosed |
| EP-0711180-A1 | FUNCTIONALIZED TRIPODAL LIGANDS FOR IMAGING APPLICATIONS | MALLINCKRODT MEDICAL, INC. (US) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995001124-A1 | FUNCTIONALIZED TRIPODAL LIGANDS FOR IMAGING APPLICATIONS | MALLINCKRODT MEDICAL, INC. (US) | 1995-01-12 | — | — | WO | disclosed |