SCHEMBL29869432

SCHEMBL29869432

c1ccc2c(c1)-c1ccccc1C21OCCO1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP8 P40818 1/20 0.49
ALDH1A1 P00352 2/20 0.43
KMT2A Q03164 3/20 0.41
GAA P10253 3/20 0.41
MEN1 O00255 2/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 2/20 0.39
ITGA4 P13612 1/20 0.39
PDK2 Q15119 1/20 0.38
THRB P10828 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
S100A4 P26447 1/20 0.35
KDM4E B2RXH2 1/20 0.35
OPRK1 P41145 1/20 0.35
GSK3B P49841 1/20 0.35
CFTR P13569 1/20 0.33
GOPC Q9HD26 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16532992 1.00 USP8 (0.49) USP8ALDH1A1KMT2AGAAMEN1
SCHEMBL11481755 0.87 ALDH1A1 (0.46) USP8ALDH1A1KMT2AGAAMEN1
SCHEMBL18287915 0.84 MAPK1 (0.43) USP8ALDH1A1KMT2AGAAMEN1
SCHEMBL11488102 0.79 MEN1 (0.54) USP8ALDH1A1KMT2AGAAMEN1
SCHEMBL18287971 0.78 MAPK1 (0.41) USP8ALDH1A1KMT2AGAAMEN1
SCHEMBL18288037 0.78 MEN1 (0.41) USP8ALDH1A1KMT2AGAAMEN1
SCHEMBL18287973 0.77 MAPT (0.42) USP8ALDH1A1SMN1; SMN2MAPTITGA4
SCHEMBL14900346 0.76 HTR2A (0.45) USP8ALDH1A1KMT2AGAAMEN1
SCHEMBL21709999 0.76 ALDH1A1 (0.41) USP8ALDH1A1KMT2AGAAMEN1
SCHEMBL14113067 0.76 ALDH1A1 (0.41) USP8ALDH1A1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843853-B Composition and method for manufacturing device using the same 东洋合成工业株式会社 2022-09-20 CN disclosed