Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14113072 | 0.83 | ALDH1A1 (0.36) | ALDH1A1MAPTITGA4PDK2 | |
| SCHEMBL29824421 | 0.80 | MAPT (0.38) | ALDH1A1MAPTITGA4S100A4KMT2A | |
| SCHEMBL14113088 | 0.77 | SIGMAR1 (0.42) | ALDH1A1MAPTITGA4KMT2AUSP8 | |
| SCHEMBL29869432 | 0.76 | USP8 (0.49) | ALDH1A1MAPTITGA4S100A4KMT2A | |
| SCHEMBL16532992 | 0.76 | USP8 (0.49) | ALDH1A1MAPTITGA4S100A4KMT2A | |
| SCHEMBL14039677 | 0.75 | GRIN1 (0.45) | GRIN1GRIN2A | |
| SCHEMBL11481917 | 0.72 | LMNA (0.40) | ALDH1A1MAPTITGA4KMT2ACYP3A4 | |
| SCHEMBL14039895 | 0.67 | NPY1R (0.40) | GRIN1GRIN2A | |
| SCHEMBL14113090 | 0.67 | SCN1A (0.46) | ALDH1A1MAPTITGA4KMT2APDK2 | |
| SCHEMBL16175958 | 0.66 | MAPT (0.42) | ALDH1A1MAPTITGA4S100A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167482-A1 | mesogenic group is linked to the C-atom No. 5 of the 1,3-dioxane-5-yl group; media showing a blue phase and their use in electro-optical light modulation elements | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |