Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL6705662 | 0.89 | — | — | |
| Bicarbonate SCHEMBL1526184 | 0.89 | CA4 (0.46) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL30145601 | 0.89 | — | — | |
| Bicarbonate SCHEMBL17422 | 0.89 | CA4 (0.46) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL149204 | 0.89 | CA4 (0.60) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL3448251 | 0.89 | CA4 (0.60) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL29764190 | 0.89 | — | — | |
| Bicarbonate SCHEMBL1491908 | 0.84 | CA4 (0.42) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL3446226 | 0.84 | CA4 (0.42) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL9772350 | 0.84 | CA4 (0.42) | CA4FAHD1MEN1LDHABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173104-A1 | MANUFACTURING METHOD OF RECORDING MEDIUM, INKJET RECORDING MEDIUM, AND METHOD OF MANUFACTURING THE SAME | FUJIFILM CORPORATION (JP) | 2010-07-08 | — | — | US | disclosed |
| EP-2004416-B1 | INKJET RECORDING MEDIUM, AND METHOD OF MANUFACTURING THE SAME | FUJIFILM CORP (JP) | 2010-05-05 | — | — | EP | disclosed |
| EP-2004416-A4 | MANUFACTURING METHOD OF RECORDING MEDIUM, INKJET RECORDING MEDIUM, AND METHOD OF MANUFACTURING THE SAME | FUJIFILM CORP (JP) | 2009-08-05 | — | — | EP | disclosed |
| EP-2004416-A1 | MANUFACTURING METHOD OF RECORDING MEDIUM, INKJET RECORDING MEDIUM, AND METHOD OF MANUFACTURING THE SAME | FUJIFILM Corporation (JP) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007116776-A1 | MANUFACTURING METHOD OF RECORDING MEDIUM, INKJET RECORDING MEDIUM, AND METHOD OF MANUFACTURING THE SAME | FUJIFILM CORPORATION (JP) | 2007-10-18 | — | — | WO | disclosed |