Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1163591 | 1.00 | MET (0.47) | METPDGFRBPDGFRAKDRAKR1C3 | |
| SCHEMBL12165434 | 0.87 | MET (0.49) | METPDGFRBPDGFRAKDRALDH1A1 | |
| SCHEMBL28864726 | 0.84 | MET (0.47) | METPDGFRBPDGFRAKDRALDH1A1 | |
| SCHEMBL29869733 | 0.84 | MET (0.47) | METPDGFRBPDGFRAKDRALDH1A1 | |
| SCHEMBL29869685 | 0.84 | MET (0.47) | METPDGFRBPDGFRAKDRALDH1A1 | |
| SCHEMBL1163117 | 0.84 | MET (0.47) | METPDGFRBPDGFRAKDRALDH1A1 | |
| SCHEMBL28674604 | 0.84 | MET (0.47) | METPDGFRBPDGFRAKDRALDH1A1 | |
| SCHEMBL27988632 | 0.82 | ALDH1A1 (0.47) | METPDGFRBPDGFRAALDH1A1MEN1 | |
| SCHEMBL6518170 | 0.79 | MET (0.49) | METPDGFRBPDGFRAAKR1C3AKR1C2 | |
| SCHEMBL6520128 | 0.78 | MET (0.45) | METAKR1C3AKR1C2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107312009-B | Quinoline compound, preparation method, intermediate, pharmaceutical composition and application thereof | 上海医药集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |