Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15662540 | 1.00 | POLB (0.31) | POLBALDH1A1TSHRFGFR4KDM4E | |
| SCHEMBL8209991 | 0.82 | KDM4E (0.46) | POLBTSHRKDM4E | |
| SCHEMBL30173709 | 0.82 | KDM4E (0.46) | POLBTSHRKDM4E | |
| SCHEMBL5698106 | 0.76 | POLB (0.32) | POLBALDH1A1TSHRFGFR4 | |
| SCHEMBL5698102 | 0.76 | POLB (0.32) | POLBALDH1A1TSHRFGFR4 | |
| SCHEMBL6054554 | 0.76 | GRIK1 (0.33) | POLBALDH1A1KDM4EGMNNUSP2 | |
| SCHEMBL3651393 | 0.74 | POLB (0.35) | POLBALDH1A1TSHRFGFR4ALOX15 | |
| SCHEMBL3651390 | 0.74 | POLB (0.35) | POLBALDH1A1TSHRFGFR4ALOX15 | |
| SCHEMBL18203199 | 0.74 | POLB (0.35) | POLBALDH1A1TSHRFGFR4ALOX15 | |
| SCHEMBL7771087 | 0.72 | TSHR (0.52) | POLBALDH1A1TSHRFGFR4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3641832-B1 | NUCLEIC ACID NANOCAPSULES FOR DRUG DELIVERY AND TARGETED GENE KNOCKDOWN | UNIV CONNECTICUT (US) | 2024-09-11 | — | — | EP | claimed |
| WO-2025124584-A1 | DEGRADABLE CATIONIC LIPID CONTAINING DISULFIDE BOND AND USE THEREOF | 厦门赛诺邦格生物科技股份有限公司 | 2025-06-19 | — | — | WO | disclosed |
| WO-2025124586-A1 | DEGRADABLE CATIONIC LIPID CONTAINING DISULFIDE BOND AND USE THEREOF | 厦门赛诺邦格生物科技股份有限公司 | 2025-06-19 | — | — | WO | disclosed |
| CN-120129679-A | VHH antibody DOTA conjugates | 雅博得乐医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-119405834-A | Splice modulating antibody-drug conjugates and methods of use thereof | 卫材R&D管理有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119405832-A | Splice modulating antibody-drug conjugates and methods of use thereof | 卫材R&D管理有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119405833-A | Splice modulating antibody-drug conjugates and methods of use thereof | 卫材R&D管理有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119405831-A | Splice modulating antibody-drug conjugates and methods of use thereof | 卫材R&D管理有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-118994394-A | Anti-IL 1RAP antibodies and antibody drug conjugates | 蓝鳍生物医药公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-112218663-B | Splice modulating antibody-drug conjugates and methods of use thereof | 卫材R&D管理有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-110352074-B | Cysteine mutant antibodies for conjugation | 思进股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118339181-A | Resistin-specific antibodies and uses thereof | 首尔大学医院 | 2024-07-12 | — | — | CN | disclosed |
| CN-118176194-A | Conjugates comprising covalent binding agents for targeting intracellular proteins | 瑞择生物公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-118043042-A | Conjugate comprising a covalent binding agent for targeting intracellular KRAS G12C proteins | 瑞择生物公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-115073376-B | C in aconite root 20 Diterpene alkaloid, preparation and application thereof | 中国医学科学院药物研究所 | 2024-02-06 | — | — | CN | disclosed |
| CN-117377495-A | Non-peptide targeted therapeutic agent and use thereof | 克林提克斯医药股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-116888138-A | Radiopharmaceutical conjugate compositions and uses thereof | 瑞择生物公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116640148-A | The aconite contains sulfonic acid group C 21 Preparation and application of diterpene alkaloid | 中国医学科学院药物研究所 | 2023-08-25 | — | — | CN | disclosed |
| CN-115073376-A | C in aconite 20 Diterpene alkaloid, preparation and application thereof | 中国医学科学院药物研究所 | 2022-09-20 | — | — | CN | disclosed |