Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | LDHB | P07195 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8209991 | 1.00 | KDM4E (0.46) | KDM4ETSHRCPB1ABATLDHA | |
| SCHEMBL7771087 | 0.92 | TSHR (0.52) | KDM4ETSHRCPB1ABATLDHA | |
| SCHEMBL7771088 | 0.92 | TSHR (0.52) | KDM4ETSHRCPB1ABATLDHA | |
| SCHEMBL1234795 | 0.85 | TSHR (0.65) | KDM4ETSHRCPB1ABATLDHA | |
| SCHEMBL28938285 | 0.85 | TSHR (0.65) | KDM4ETSHRCPB1ABATLDHA | |
| SCHEMBL4115859 | 0.85 | TSHR (0.65) | KDM4ETSHRCPB1ABATLDHA | |
| SCHEMBL30461050 | 0.85 | TSHR (0.65) | KDM4ETSHRCPB1ABATLDHA | |
| SCHEMBL15662540 | 0.82 | POLB (0.31) | KDM4ETSHRPOLB | |
| SCHEMBL29871199 | 0.82 | POLB (0.31) | KDM4ETSHRPOLB | |
| SCHEMBL24180793 | 0.81 | KDM4E (0.43) | KDM4ETSHRCPB1ABATGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025041102-A1 | TARGETED IMMUNE ACTIVATION WITH IL-18 IMMUNOCYTOKINES | BRIGHT PEAK THERAPEUTICS AG (CH) | 2025-02-27 | — | — | WO | disclosed |
| CN-119053347-A | Immune antigen specific IL-18 immunocytokine and uses thereof | 明峰治疗股份公司 | 2024-11-29 | — | — | CN | disclosed |
| EP-4366778-A1 | ANTIBODY CONJUGATES AND MANUFACTURE THEREOF | Bright Peak Therapeutics AG (CH) | 2024-05-15 | — | — | EP | disclosed |
| CN-117615792-A | Conjugates of checkpoint inhibitors with IL-2 and uses thereof | 明峰治疗股份公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117615794-A | Checkpoint inhibitors conjugated to IL-2 and uses thereof | 明峰治疗股份公司 | 2024-02-27 | — | — | CN | disclosed |
| WO-2023281481-A1 | ANTIBODY CONJUGATES AND MANUFACTURE THEREOF | BRIGHT PEAK THERAPEUTICS (CH) | 2023-01-12 | — | — | WO | disclosed |