SCHEMBL29871710

SCHEMBL29871710

CC(C)[C@H](N)C(=O)N[C@@H](Cc1cn(C)c2ccccc12)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 3/20 0.53
▸ CTSS P25774 3/20 0.53
▸ CTSK P43235 3/20 0.53
▸ CTSH P09668 1/20 0.52
▸ NPBWR1 P48145 1/20 0.51
▸ GLP1R P43220 9/20 0.50
▸ CXCR4 P61073 2/20 0.49
▸ IL23R Q5VWK5 2/20 0.49
▸ GRPR P30550 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29670477 0.96 NPBWR1 (0.56) CTSLCTSSCTSKCTSHNPBWR1
SCHEMBL30216222 0.95 GLP1R (0.52) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL30063985 0.94 GLP1R (0.54) CTSLCTSSCTSKNPBWR1GLP1R
SCHEMBL29613390 0.93 IL23R (0.55) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL30183034 0.91 GLP1R (0.55) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL29484313 0.90 NPBWR1 (0.55) CTSLCTSSCTSKCTSHNPBWR1
SCHEMBL29484310 0.90 CTSL (0.53) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL30064553 0.89 GLP1R (0.58) GLP1RIL23RGRPR
SCHEMBL29740507 0.87 IL23R (0.48) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL29489380 0.87 CTSL (0.53) CTSLCTSSCTSKCTSHNPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220249706-A1 VIRAL VECTOR THERAPY APELLIS PHARMACEUTICALS, INC. (US) 2022-08-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220249706-A1 VIRAL VECTOR THERAPY CFH, CFB, HAVCR2 CTSL 761/4885CTSS 564/4885CTSK 1048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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