Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1065451 | 0.87 | GAA (0.47) | GAACCR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL719799 | 0.86 | CCR2 (0.58) | GAACCR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2979314 | 0.86 | GAA (0.65) | GAACCR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2971927 | 0.81 | CCR2 (0.69) | GAACCR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL3316845 | 0.79 | ALOX15 (0.44) | GAACCR2SMN1; SMN2POLBKMT2A | |
| SCHEMBL5172985 | 0.79 | ALOX15 (0.44) | GAACCR2SMN1; SMN2POLBKMT2A | |
| SCHEMBL3318233 | 0.76 | HPGD (0.37) | GAACCR2SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL3316925 | 0.71 | CCR2 (0.60) | CCR2EPHX1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL14503263 | 0.69 | GAA (0.79) | GAACCR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1080974 | 0.69 | CCR2 (0.58) | GAACCR2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229184-A2 | ANTI-INFLAMMATORY COMPOSITIONS AND COMBINATIONS | Cambridge Enterprise Ltd. (GB) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009074794-A2 | ANTI-INFLAMMATORY COMPOSITIONS AND COMBINATIONS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2009-06-18 | — | — | WO | disclosed |