Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 10/20 | 0.94 |
| ▸ | ADRA1D | P25100 | 9/20 | 0.94 |
| ▸ | ADRA1B | P35368 | 9/20 | 0.94 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.94 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.94 |
| ▸ | HTR1A | P08908 | 2/20 | 0.94 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.94 |
| ▸ | DRD2 | P14416 | 2/20 | 0.94 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.94 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.94 |
| ▸ | HTR2A | P28223 | 2/20 | 0.94 |
| ▸ | DRD3 | P35462 | 2/20 | 0.94 |
| ▸ | HTR2B | P41595 | 2/20 | 0.94 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.94 |
| ▸ | HTR7 | P34969 | 1/20 | 0.94 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.94 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tamsulosin SCHEMBL3343160 | 0.97 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL29566149 | 0.97 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL30361066 | 0.97 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL30465862 | 0.97 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL34378 | 0.97 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL29588704 | 0.97 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL53998 | 0.97 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL29363851 | 0.97 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL29599595 | 0.97 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL23428 | 0.96 | ADRA1A (0.98) | ADRA1AADRA1DADRA1BADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884734-B2 | Anti-MET antibodies and methods of use thereof | CELLDEX THERAPEUTICS, INC. (US) | 2024-01-30 | — | — | US | disclosed |
| US-11427632-B2 | Antibodies with low immunogenicity and uses thereof | CELGENE CORPORATION (US) | 2022-08-30 | — | — | US | disclosed |