Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tamsulosin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 10/20 | 1.00 |
| ▸ | ADRA1D known ✓ | P25100 | 9/20 | 1.00 |
| ▸ | ADRA1B known ✓ | P35368 | 9/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 4/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 2/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | DRD2 | P14416 | 2/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 2/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 2/20 | 1.00 |
| ▸ | HTR2A | P28223 | 2/20 | 1.00 |
| ▸ | DRD3 | P35462 | 2/20 | 1.00 |
| ▸ | HTR2B | P41595 | 2/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 1.00 |
| ▸ | HTR7 | P34969 | 1/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 1/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tamsulosin SCHEMBL34378 | 1.00 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL30361066 | 1.00 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL3343160 | 1.00 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL29599595 | 1.00 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL29363851 | 1.00 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL53998 | 1.00 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL30465862 | 1.00 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL29566149 | 1.00 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL1560198 | 0.99 | ADRA1A (0.98) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL2315085 | 0.99 | ADRA1A (0.98) | ADRA1AADRA1DADRA1BADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12366138-B2 | Hydrogen production, storage and recovery | TerraH2 LLC (US) | 2025-07-22 | — | — | US | claimed |
| CN-119950913-A | Ventilator trigger control method, system, equipment and storage medium based on flow rate | 深圳市科曼医疗设备有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-118411271-B | Multi-point linkage area scheduling system based on secondary residual chlorine guarantee coupling peak staggering | 福州智水匠数字科技有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-118567316-A | System for preparing methanol by water electrolysis hydrogen and oxygen coupling oxygen-enriched combustion and scheduling method thereof | 浙江英集动力科技有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-118416352-A | Method and device for controlling gas flow rate of breathing machine and breathing machine | 深圳市科曼医疗设备有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-117800935-A | Method for synthesizing chiral phthaloyl ester compound by dynamic kinetic resolution | 河南师范大学 | 2024-04-02 | — | — | CN | claimed |
| US-20220251935-A1 | HYDROGEN PRODUCTION, STORAGE AND RECOVERY | TerraH2 LLC | 2022-08-11 | — | — | US | claimed |
| CN-114688182-A | Clutch protection control method, double-clutch automatic transmission and vehicle | 中国第一汽车股份有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-114580283-A | Numerical simulation method for medium-and long-term dynamic landform evolution of mountain stream strong tide river mouth branch section | 水利部交通运输部国家能源局南京水利科学研究院 | 2022-06-03 | — | — | CN | claimed |
| CN-110457848-B | Method for calculating hydrostatic level of tail water lock chamber in non-pressure tail water system | 中国电建集团成都勘测设计研究院有限公司 | 2022-05-03 | — | — | CN | claimed |
| WO-2026104380-A1 | SOLVENT-ASSISTED CONVERSION OF SOLID ORGANIC WASTE TO HIGH VALUE CHEMICALS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2026-05-21 | — | — | WO | disclosed |
| US-12631357-B2 | Building equipment with predictive control | TYCO FIRE & SECURITY GMBH (CH) | 2026-05-19 | — | — | US | disclosed |
| CN-122062765-A | Data processing method and equipment based on ultrasonic water flow measurement and storage medium | 成都长城开发科技股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-122062766-A | Water flow testing method and device based on ultrasonic wave and storage medium | 成都长城开发科技股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-121586758-A | Process for converting pyrolysis oil, wax and/or oligomers to higher value chemicals | 沙特基础工业公司(SABIC)全球技术有限公司 | 2026-02-27 | — | — | CN | disclosed |
| CN-114580283-A | Numerical simulation method for medium-and long-term dynamic landform evolution of mountain stream strong tide river mouth branch section | 水利部交通运输部国家能源局南京水利科学研究院 | 2022-06-03 | — | — | CN | disclosed |
| US-11346572-B2 | Building equipment with predictive control | Johnson Controls Tyco IP Holdings LLP (US) | 2022-05-31 | — | — | US | disclosed |
| US-20220135633-A1 | METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS | ON TARGET THERAPEUTICS LLC | 2022-05-05 | — | — | US | disclosed |
| CN-110457848-B | Method for calculating hydrostatic level of tail water lock chamber in non-pressure tail water system | 中国电建集团成都勘测设计研究院有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-111067494-B | Microcirculation resistance rapid calculation method based on blood flow reserve fraction and blood flow resistance model | 西北工业大学 | 2022-04-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135633-A1 | METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS | LDLR, HDLBP, LIPG | ADRA1A 2411/4885ADRA1D 3086/4885ADRA1B 3117/4885 |
| US-12631357-B2 | Building equipment with predictive control | VDAC3, VDAC2, HVCN1 | ADRA1A 4028/4885ADRA1D 3217/4885ADRA1B 4502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.