Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 2/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17602275 | 1.00 | MC4R (0.50) | MC4RKDM4CDRD4KDM4EALDH1A1 | |
| SCHEMBL28176530 | 0.89 | ALDH1A1 (0.49) | KDM4CDRD4KDM4EALDH1A1MAPT | |
| SCHEMBL28176509 | 0.85 | CHRM3 (0.49) | DRD4 | |
| SCHEMBL17602174 | 0.83 | NPC1 (0.69) | MC4RKDM4CKDM4EALDH1A1MAPT | |
| SCHEMBL20251418 | 0.82 | KDM4E (0.57) | MC4RKDM4CKDM4EALDH1A1NPC1 | |
| SCHEMBL10370696 | 0.79 | MC4R (0.62) | MC4RKDM4EALDH1A1MAPTCHKA | |
| SCHEMBL17602218 | 0.78 | HTR2C (0.50) | KDM4CDRD2DRD3 | |
| SCHEMBL29542054 | 0.78 | HTR2C (0.50) | KDM4CDRD2DRD3 | |
| SCHEMBL13535291 | 0.77 | MC4R (0.74) | MC4RKDM4EALDH1A1MAPTCHKA | |
| SCHEMBL6030631 | 0.76 | SIGMAR1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3453710-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-09-21 | — | — | EP | disclosed |