Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 2/20 | 0.52 |
| ▸ | CFD | P00746 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042882 | 1.00 | METTL3 (0.52) | METTL3CFDP2RX3DHODHMETTL14 | |
| SCHEMBL1042881 | 1.00 | METTL3 (0.52) | METTL3CFDP2RX3DHODHMETTL14 | |
| SCHEMBL1044585 | 0.94 | METTL3 (0.54) | METTL3CFDP2RX3METTL14P2RX7 | |
| SCHEMBL1044583 | 0.94 | METTL3 (0.54) | METTL3CFDP2RX3METTL14P2RX7 | |
| SCHEMBL1077174 | 0.92 | METTL3 (0.58) | METTL3CFDPDE10A | |
| SCHEMBL1077172 | 0.92 | METTL3 (0.58) | METTL3CFDPDE10A | |
| SCHEMBL3243702 | 0.92 | METTL3 (0.43) | METTL3 | |
| SCHEMBL1046216 | 0.92 | METTL3 (0.51) | METTL3MRGPRX4CHRM1 | |
| SCHEMBL1046215 | 0.92 | METTL3 (0.51) | METTL3MRGPRX4CHRM1 | |
| SCHEMBL1045444 | 0.92 | METTL3 (0.53) | METTL3CFDP2RX3METTL14P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4059923-A1 | 4-OXOQUINOLINE COMPOUND AND USE THEREOF AS HIV INTEGRASE INHIBITOR | Japan Tobacco Inc. (JP) | 2022-09-21 | — | — | EP | disclosed |