SCHEMBL3243702

SCHEMBL3243702

CCC[C@@H](CO)n1cc(OC(=O)O)c(=O)c2cc(Cc3cccc(Cl)c3F)cc(OC(C)C)c21

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
METTL3 Q86U44 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3242298 0.94 METTL3 (0.44) METTL3
SCHEMBL3241563 0.92 METTL3 (0.48) METTL3
SCHEMBL3245711 0.92 METTL3 (0.42) METTL3
SCHEMBL1042881 0.92 METTL3 (0.52) METTL3
SCHEMBL29875296 0.92 METTL3 (0.52) METTL3
SCHEMBL1042882 0.92 METTL3 (0.52) METTL3
SCHEMBL3239885 0.90 METTL3 (0.48) METTL3
SCHEMBL3237655 0.88 METTL3 (0.54) METTL3
SCHEMBL3241874 0.87 METTL3 (0.45) METTL3
SCHEMBL3240029 0.86 METTL3 (0.49) METTL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1564210-B9 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS JAPAN TOBACCO INC (JP) 2010-03-31 EP claimed
EP-1564210-B1 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS JAPAN TOBACCO INC (JP) 2009-09-16 EP claimed