Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24279790 | 1.00 | FAAH (0.43) | FAAHSLC6A5SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23071837 | 0.95 | FAAH (0.46) | FAAHSLC6A5SMN1; SMN2EPHX2MME | |
| SCHEMBL19569859 | 0.86 | FAAH (0.54) | FAAHSLC6A5SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30076306 | 0.86 | FAAH (0.60) | FAAHSLC6A5SMN1; SMN2ALDH1A1MME | |
| SCHEMBL29789543 | 0.85 | MME (0.42) | SMN1; SMN2MMEACECPA1ACE2 | |
| SCHEMBL6447833 | 0.84 | EPHX2 (0.50) | FAAHSLC6A5SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL6447837 | 0.84 | EPHX2 (0.50) | FAAHSLC6A5SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL30018188 | 0.84 | FAAH (0.62) | FAAHSLC6A5SMN1; SMN2ALDH1A1 | |
| SCHEMBL30018617 | 0.84 | FAAH (0.62) | FAAHSLC6A5SMN1; SMN2ALDH1A1 | |
| SCHEMBL30018433 | 0.83 | FAAH (0.45) | FAAHSLC6A5SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313033-A1 | BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS | TRUSTEES OF TUFTS COLLEGE (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-117425476-A | Boric acid compounds, compositions and methods | 塔夫茨大学的受托人 | 2024-01-19 | — | — | CN | disclosed |
| EP-4126053-A1 | FAP-TARGETED RADIOPHARMACEUTICALS AND IMAGING AGENTS, AND USES RELATED THERETO | TRUSTEES OF TUFTS COLLEGE (US) | 2023-02-08 | — | — | EP | disclosed |
| CN-115697413-A | Radiopharmaceuticals and imaging agents targeting FAP and uses related thereto | 塔夫茨大学信托人 | 2023-02-03 | — | — | CN | disclosed |
| WO-2022204368-A1 | BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS | TRUSTEES OF TUFTS COLLEGE (US) | 2022-09-29 | — | — | WO | disclosed |