Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24279790 | 0.95 | FAAH (0.43) | FAAHSLC6A5SMN1; SMN2CASP1EPHX2 | |
| SCHEMBL29876243 | 0.95 | FAAH (0.43) | FAAHSLC6A5SMN1; SMN2CASP1EPHX2 | |
| SCHEMBL30076306 | 0.88 | FAAH (0.60) | FAAHSLC6A5SMN1; SMN2MMEACE | |
| SCHEMBL30018617 | 0.86 | FAAH (0.62) | FAAHSLC6A5SMN1; SMN2PLA2G2APLA2G5 | |
| SCHEMBL30018188 | 0.86 | FAAH (0.62) | FAAHSLC6A5SMN1; SMN2PLA2G2APLA2G5 | |
| SCHEMBL9812251 | 0.86 | FAAH (0.54) | FAAHSLC6A5SMN1; SMN2NMT2NMT1 | |
| SCHEMBL10768725 | 0.85 | FAAH (0.59) | FAAHSLC6A5SMN1; SMN2NMT2NMT1 | |
| SCHEMBL18924154 | 0.85 | FAAH (0.43) | FAAHSLC6A5SMN1; SMN2CASP1EPHX2 | |
| SCHEMBL17570945 | 0.85 | FAAH (0.43) | FAAHSLC6A5SMN1; SMN2CASP1EPHX2 | |
| SCHEMBL23071799 | 0.84 | NMT2 (0.45) | CASP1NMT2NMT1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163458-A1 | NOVEL CRYPTOPHYCIN COMPOUNDS AND CONJUGATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI SA (FR) | 2021-06-03 | — | — | US | disclosed |
| US-10941139-B2 | Cryptophycin compounds and conjugates, their preparation and their therapeutic use | SANOFI (FR) | 2021-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163458-A1 | NOVEL CRYPTOPHYCIN COMPOUNDS AND CONJUGATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | XPOT, HCCS, COIL | FAAH 4805/4885SLC6A5 3998/4885SMN1; SMN2 3355/4885 |
| US-10941139-B2 | Cryptophycin compounds and conjugates, their preparation and their therapeutic use | XPOT, COIL, HCCS | FAAH 4770/4885SLC6A5 3793/4885SMN1; SMN2 3003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.