Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CREB1 | P16220 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28848502 | 1.00 | BCHE (0.48) | BCHEACHEL3MBTL1CREB1CYP1A1 | |
| SCHEMBL28848493 | 0.82 | CDK2 (0.42) | BCHEACHEL3MBTL1CYP1A1CYP1A2 | |
| SCHEMBL28848503 | 0.81 | BCHE (0.48) | BCHEACHEL3MBTL1CREB1CYP1A1 | |
| SCHEMBL28848526 | 0.81 | ACHE (0.60) | BCHEACHEL3MBTL1CREB1CYP1A1 | |
| SCHEMBL29195640 | 0.80 | BCHE (0.47) | BCHEACHEL3MBTL1CREB1CYP1A1 | |
| SCHEMBL25301059 | 0.74 | ABCB1 (0.65) | BCHEACHEL3MBTL1CREB1CYP1A1 | |
| SCHEMBL28848659 | 0.72 | ACHE (0.67) | BCHEACHECREB1CYP1A1CYP1A2 | |
| SCHEMBL22667444 | 0.72 | ABCB1 (0.54) | BCHEACHEL3MBTL1CREB1CYP1A1 | |
| SCHEMBL28848654 | 0.69 | KDM5A (0.52) | BCHEACHECYP1A2MAPTABCB1 | |
| SCHEMBL28848656 | 0.68 | ACHE (0.51) | BCHEACHEL3MBTL1CREB1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957182-B | USP8 inhibitor containing flavone skeleton structure and application thereof | 中国药科大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-114957182-A | USP8 inhibitor containing flavone skeleton structure and application thereof | 中国药科大学 | 2022-08-30 | — | — | CN | disclosed |