Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | CREB1 | P16220 | 2/20 | 0.63 |
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | PLK1 | P53350 | 2/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.59 |
| ▸ | GABRP | O00591 | 3/20 | 0.55 |
| ▸ | GABRD | O14764 | 3/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.55 |
| ▸ | GABRE | P78334 | 3/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28848526 | 0.92 | ACHE (0.60) | ABCB1MAPTCREB1ACHEBCHE | |
| SCHEMBL22667444 | 0.90 | ABCB1 (0.54) | ABCB1MAPTCREB1ACHEBCHE | |
| SCHEMBL21335354 | 0.86 | ACHE (0.77) | ABCB1MAPTCREB1ACHEBCHE | |
| SCHEMBL27797164 | 0.83 | CREB1 (0.76) | ABCB1MAPTCREB1ACHEBCHE | |
| Isowogonin SCHEMBL28012275 | 0.83 | ACHE (0.79) | ABCB1MAPTCREB1ACHEPLK1 | |
| SCHEMBL30852784 | 0.81 | CREB1 (0.77) | ABCB1MAPTCREB1ACHEBCHE | |
| SCHEMBL28848659 | 0.80 | ACHE (0.67) | ABCB1MAPTCREB1ACHEBCHE | |
| Norwogonin SCHEMBL30485998 | 0.79 | GABRP (0.68) | ABCB1MAPTCREB1ACHEPLK1 | |
| Norwogonin SCHEMBL760431 | 0.79 | GABRP (0.68) | ABCB1MAPTCREB1ACHEPLK1 | |
| SCHEMBL30376285 | 0.79 | MAPT (1.00) | ABCB1MAPTCREB1ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293414-A1 | USE OF CYCLIN-DEPENDENT KINASE (CDK) INHIBITORS FOR THE SLOWDOWN OR PREVENTION OF BIOLOGICAL AGING | HOPE PERMANENTE LLC (US) | 2023-09-21 | — | — | US | claimed |
| EP-4582100-A1 | MEDICAMENT FOR TREATMENT AND/OR PREVENTION OF CANCER | Toray Industries, Inc. (JP) | 2025-07-09 | — | — | EP | disclosed |
| CN-119789868-A | Medicine for treating and/or preventing cancer | 东丽株式会社 | 2025-04-08 | — | — | CN | disclosed |
| WO-2024048541-A1 | MEDICAMENT FOR TREATMENT AND/OR PREVENTION OF CANCER | 東レ株式会社 | 2024-03-07 | — | — | WO | disclosed |
| US-20230293414-A1 | USE OF CYCLIN-DEPENDENT KINASE (CDK) INHIBITORS FOR THE SLOWDOWN OR PREVENTION OF BIOLOGICAL AGING | HOPE PERMANENTE LLC (US) | 2023-09-21 | — | — | US | disclosed |
| EP-4192463-A1 | USE OF CYCLIN-DEPENDENT KINASE (CDK) INHIBITORS FOR THE SLOWDOWN OR PREVENTION OF BIOLOGICAL AGING | Hope Permanente, LLC (US) | 2023-06-14 | — | — | EP | disclosed |
| CN-113171467-B | Chimeric molecule based on NQO1 regulation and control and application thereof | 中国科学院化学研究所 | 2023-04-07 | — | — | CN | disclosed |