Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29876668 | 0.78 | ALDH1A1 (0.51) | AKT1AKT2ALDH1A1 | |
| SCHEMBL29877183 | 0.77 | SLC2A1 (0.42) | ALDH1A1 | |
| SCHEMBL14572618 | 0.71 | — | — | |
| SCHEMBL14561625 | 0.71 | — | — | |
| SCHEMBL14572065 | 0.70 | — | — | |
| SCHEMBL14561673 | 0.69 | — | — | |
| SCHEMBL13920968 | 0.69 | MAPK14 (0.60) | — | |
| SCHEMBL14561027 | 0.69 | — | — | |
| SCHEMBL14561203 | 0.69 | — | — | |
| SCHEMBL14561248 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022213975-A1 | COMPOUNDS TARGETING Y220C MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-10-13 | — | — | WO | disclosed |