Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29876498 | 0.77 | AKT1 (0.44) | ALDH1A1 | |
| SCHEMBL14561531 | 0.69 | — | — | |
| SCHEMBL17605614 | 0.68 | BCHE (0.54) | MAP4K4 | |
| SCHEMBL29876668 | 0.68 | ALDH1A1 (0.51) | KDM4EALDH1A1 | |
| SCHEMBL14561533 | 0.67 | — | — | |
| SCHEMBL14561464 | 0.67 | — | — | |
| SCHEMBL28467365 | 0.66 | CARM1 (0.56) | ALDH1A1MAP4K4MAPK1 | |
| SCHEMBL14561543 | 0.65 | — | — | |
| SCHEMBL375105 | 0.62 | KDM1A (0.48) | MAP4K4PDCD1CD274 | |
| SCHEMBL8816266 | 0.62 | KDM1A (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022213975-A1 | COMPOUNDS TARGETING Y220C MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-10-13 | — | — | WO | disclosed |