Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2346449 | 0.79 | KMT2A (0.52) | NPSR1TSHRUSP2LMNASMN1; SMN2 | |
| SCHEMBL29876546 | 0.76 | MAPT (0.39) | RXFP1TP53MAPTPOLBKMT2A | |
| SCHEMBL29876743 | 0.76 | HTR2C (0.51) | KDM4EMAPTKMT2AHTR2CMEN1 | |
| SCHEMBL5470276 | 0.74 | KMT2A (0.55) | NPSR1TSHRUSP2LMNASMN1; SMN2 | |
| Bromide SCHEMBL11364490 | 0.72 | KMT2A (0.53) | NPSR1TSHRUSP2LMNASMN1; SMN2 | |
| SCHEMBL31472212 | 0.72 | NPC1 (0.45) | L3MBTL1MAPTKMT2A | |
| SCHEMBL21577669 | 0.71 | HTR2C (0.60) | HTR2C | |
| SCHEMBL1762390 | 0.68 | CYP11B1 (0.57) | L3MBTL1KMT2A | |
| SCHEMBL9829355 | 0.68 | MEN1 (0.33) | TSHRKMT2AMEN1 | |
| SCHEMBL29876793 | 0.66 | NPC1 (0.57) | TSHRLMNAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022213975-A1 | COMPOUNDS TARGETING Y220C MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-10-13 | — | — | WO | disclosed |