SCHEMBL29877142

SCHEMBL29877142

Brc1cc(I)cc(-c2ccccc2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
MAPK1 P28482 2/20 0.48
CRHBP P24387 1/20 0.45
CRHR2 Q13324 1/20 0.45
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
TSHR P16473 2/20 0.37
TP53 P04637 1/20 0.37
IDO1 P14902 1/20 0.37
AKR1C3 P42330 2/20 0.36
AKR1C2 P52895 2/20 0.36
AKR1C1 Q04828 2/20 0.36
AKR1C4 P17516 1/20 0.36
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2163690 1.00 ALDH1A1 (0.48) ALDH1A1MAPK1CRHBPCRHR2SLC6A2
SCHEMBL45718 0.83 ALDH1A1 (0.60) ALDH1A1MAPK1CRHBPCRHR2SLC6A2
SCHEMBL16901964 0.83 ALDH1A1 (0.53) ALDH1A1MAPK1CRHBPCRHR2SLC6A4
SCHEMBL21892151 0.83 ALDH1A1 (0.53) ALDH1A1MAPK1CRHBPCRHR2SLC6A4
SCHEMBL1562747 0.83 ALDH1A1 (0.60) ALDH1A1MAPK1CRHBPCRHR2SLC6A2
SCHEMBL2194491 0.83 ALDH1A1 (0.53) ALDH1A1MAPK1CRHBPCRHR2SLC6A4
SCHEMBL15358382 0.80 ALDH1A1 (0.65) ALDH1A1MAPK1CRHBPCRHR2SLC6A2
Phosphine SCHEMBL28191580 0.80 ALDH1A1 (0.50) ALDH1A1MAPK1CRHBPCRHR2SLC6A4
SCHEMBL12996631 0.80 ALDH1A1 (0.57) ALDH1A1MAPK1CRHBPCRHR2SLC6A2
SCHEMBL18552200 0.80 ALDH1A1 (0.65) ALDH1A1MAPK1CRHBPCRHR2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110563767-B Organometallic compound, organic light emitting device and diagnostic composition including the same 三星电子株式会社 2024-01-05 CN disclosed
CN-113380954-B Organic electroluminescent device and electronic apparatus 陕西莱特光电材料股份有限公司 2022-11-29 CN disclosed
CN-109415315-B Compound for organic electric element, organic electric element using same, and electronic device using same 德山新勒克斯有限公司 2022-06-28 CN disclosed