SCHEMBL45718

SCHEMBL45718

Brc1cc(-c2ccccc2)cc(-c2ccccc2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
MAPK1 P28482 2/20 0.60
CRHBP P24387 1/20 0.54
CRHR2 Q13324 1/20 0.54
TDP1 Q9NUW8 2/20 0.47
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
AKR1C3 P42330 2/20 0.42
AKR1C2 P52895 2/20 0.42
AKR1C1 Q04828 2/20 0.42
AKR1C4 P17516 1/20 0.42
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
MCL1 Q07820 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15358382 0.97 ALDH1A1 (0.65) ALDH1A1MAPK1CRHBPCRHR2TDP1
SCHEMBL12996631 0.97 ALDH1A1 (0.57) ALDH1A1MAPK1CRHBPCRHR2TDP1
SCHEMBL18552200 0.97 ALDH1A1 (0.65) ALDH1A1MAPK1CRHBPCRHR2TDP1
SCHEMBL20955800 0.95 ALDH1A1 (0.55) ALDH1A1MAPK1CRHBPCRHR2TDP1
SCHEMBL23135172 0.95 ALDH1A1 (0.55) ALDH1A1MAPK1CRHBPCRHR2TDP1
SCHEMBL1562747 0.94 ALDH1A1 (0.60) ALDH1A1MAPK1CRHBPCRHR2TDP1
SCHEMBL3888756 0.92 ALDH1A1 (0.52) ALDH1A1MAPK1CRHBPCRHR2TDP1
SCHEMBL24767666 0.92 ALDH1A1 (0.59) ALDH1A1MAPK1CRHBPCRHR2TDP1
SCHEMBL18419158 0.92 ALDH1A1 (0.59) ALDH1A1MAPK1CRHBPCRHR2TDP1
SCHEMBL24751331 0.92 ALDH1A1 (0.59) ALDH1A1MAPK1CRHBPCRHR2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 950 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581071-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2025-07-09 EP claimed
WO-2024046712-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-03-07 WO claimed
CN-113621131-B Polyelectrolyte material, preparation method thereof and polyelectrolyte membrane 中国科学技术大学 2022-10-28 CN claimed
CN-113621131-A Polyelectrolyte material, preparation method thereof and polyelectrolyte membrane 中国科学技术大学 2021-11-09 CN claimed
CN-109824474-A The preparation method of one kind 3,5- diphenyl bromobenzene 辽宁博美医药科技有限公司 2019-05-31 CN claimed
CN-122094304-A Organic electroluminescent device and electronic device 2026-05-26 CN disclosed
CN-122080005-A Organic material, organic electroluminescent device and electronic device 2026-05-26 CN disclosed
WO-2026103549-A1 ORGANIC MATERIAL, COMPOSITION, ORGANIC ELECTROLUMINESCENT APPARATUS AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2026-05-21 WO disclosed
CN-122036693-A Organic material, composition, organic electroluminescent device, and electronic device 陕西莱特光电材料股份有限公司 2026-05-15 CN disclosed
US-20260123169-A1 COMPOSITION FOR ORGANIC LIGHT EMITTING DEVICE AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEMICAL LTD (KR) 2026-04-30 US disclosed
US-20260101669-A1 LIGHT-EMITTING ELEMENT, MONOAMINE COMPOUND FOR THE LIGHT-EMITTING ELEMENT, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING ELEMENT SAMSUNG DISPLAY CO LTD (KR) 2026-04-09 US disclosed
EP-4722202-A1 LIGHT-EMITTING ELEMENT, MONOAMINE COMPOUND FOR THE LIGHT-EMITTING ELEMENT, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING ELEMENT Samsung Display Co., Ltd. (KR) 2026-04-08 EP disclosed
EP-1009041-A2 Electroluminescent device with improved hole transport layer EASTMAN KODAK COMPANY (US) 2000-06-14 EP disclosed
EP-1009044-A2 Electroluminescent device with anthracene derivatives hole transport layer EASTMAN KODAK COMPANY (US) 2000-06-14 EP disclosed
EP-0952200-A2 Organic electroluminescent elements for stable blue electroluminescent devices EASTMAN KODAK COMPANY (US) 1999-10-27 EP disclosed
US-5972247-A FOR BLUE ELECTROLUMINESCENT DEVICES; FLAT PANEL DISPLAYS EASTMAN KODAK COMPANY (US) 1999-10-26 US disclosed
EP-0579797-B1 DIPHOSPHINE LIGANDS HOFFMANN LA ROCHE (CH) 1999-04-21 EP disclosed
US-5457219-A Used in making hydrogenation catalysts and isomerization catalysts HOFFMANN-LA ROCHE INC. (US) 1995-10-10 US disclosed
EP-0579797-A1 DIPHOSPHINE LIGANDS F. HOFFMANN-LA ROCHE AG (CH) 1994-01-26 EP disclosed
WO-1993015091-A1 DIPHOSPHINE LIGANDS F. HOFFMANN-LA ROCHE AG (CH) 1993-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260123169-A1 COMPOSITION FOR ORGANIC LIGHT EMITTING DEVICE AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, AHR, CRY2 ALDH1A1 105/4885MAPK1 2368/4885CRHBP 3793/4885
US-20260101669-A1 LIGHT-EMITTING ELEMENT, MONOAMINE COMPOUND FOR THE LIGHT-EMITTING ELEMENT, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING ELEMENT SLC18A1, MAOA, SLC1A2 ALDH1A1 139/4885MAPK1 700/4885CRHBP 580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.