Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26968777 | 1.00 | BACE1 (0.33) | BACE1CCR1CCR5CCR8RAB9A | |
| SCHEMBL557234 | 0.75 | CCR1 (0.52) | BACE1CCR1CCR5CCR8RAB9A | |
| SCHEMBL29407003 | 0.75 | CCR1 (0.52) | BACE1CCR1CCR5CCR8RAB9A | |
| SCHEMBL29966934 | 0.75 | BACE1 (0.41) | BACE1RAB9AKDM4EMAPTRXFP1 | |
| SCHEMBL28874637 | 0.75 | BACE1 (0.41) | BACE1RAB9AKDM4EMAPTRXFP1 | |
| SCHEMBL28874631 | 0.72 | CYP1A2 (0.39) | BACE1RAB9AKDM4EPPARGSMN1; SMN2 | |
| SCHEMBL9980542 | 0.72 | EGFR (0.37) | — | |
| SCHEMBL140968 | 0.70 | LMNA (0.54) | CCR1CCR5CCR8RAB9AKDM4E | |
| SCHEMBL28864557 | 0.70 | CCR1 (0.46) | BACE1CCR1CCR5CCR8RAB9A | |
| Hydrochloric Acid SCHEMBL9299437 | 0.70 | EGFR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294805-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | Regents of the University of Minnesota (US) | 2023-12-27 | — | — | EP | disclosed |
| WO-2022178437-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-08-25 | — | — | WO | disclosed |