SCHEMBL140968

SCHEMBL140968

c1cnc2c(c1)ccc1ncsc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
CCR1 P32246 3/20 0.54
CCR5 P51681 3/20 0.54
CCR8 P51685 3/20 0.54
MMP2 P08253 2/20 0.54
TSHR P16473 2/20 0.54
CYP3A4 P08684 2/20 0.54
KDM4E B2RXH2 1/20 0.54
GMNN O75496 1/20 0.54
TP53 P04637 1/20 0.54
HSP90AA1 P07900 1/20 0.54
CYP2D6 P10635 1/20 0.54
MAPT P10636 1/20 0.54
MMP9 P14780 1/20 0.54
ALOX15 P16050 1/20 0.54
NFKB1 P19838 1/20 0.54
MMP8 P22894 1/20 0.54
THPO P40225 1/20 0.54
MTOR P42345 1/20 0.54
HTT P42858 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28958656 0.98 LMNA (0.52) LMNACCR1CCR5CCR8MMP2
SCHEMBL2809624 0.74 KDM4E (0.45) LMNACCR1CCR5CCR8MMP2
SCHEMBL23218293 0.73 KDM4E (0.58) LMNACCR1CCR5CCR8MMP2
SCHEMBL2852558 0.73 CYP3A4 (0.47) LMNATSHRCYP3A4KDM4EMAPT
SCHEMBL3943646 0.73 MAPT (0.58) LMNATSHRCYP3A4KDM4ETP53
SCHEMBL9980542 0.73 EGFR (0.37) ALDH1A1
Phenanthroline SCHEMBL29367277 0.72 CCR1 (1.00) LMNACCR1CCR5CCR8MMP2
Phenanthroline SCHEMBL29354015 0.72 CCR1 (1.00) LMNACCR1CCR5CCR8MMP2
Phenanthroline SCHEMBL8845760 0.72 CCR1 (1.00) LMNACCR1CCR5CCR8MMP2
Phenanthroline SCHEMBL8312 0.72 CCR1 (1.00) LMNACCR1CCR5CCR8MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 847 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034237-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME GENMAB AS (DK) 2026-02-05 US claimed
US-20260034238-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME GENMAB AS (DK) 2026-02-05 US claimed
EP-4648800-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-11-19 EP claimed
EP-4648801-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-11-19 EP claimed
EP-4608451-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-09-03 EP claimed
US-20250115680-A1 PTK7 BINDING AGENTS, CONJUGATES THEREOF AND METHODS OF USING THE SAME WILMINGTON TRUST, NATIONAL ASSOCIATION 2025-04-10 US claimed
WO-2024151890-A9 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-08-22 WO claimed
WO-2024149345-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-07-18 WO claimed
WO-2024151890-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-07-18 WO claimed
EP-4366777-A2 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-05-15 EP claimed
EP-1296644-A2 SYSTEMS AND METHODS FOR TREATING A MUCOSAL SURFACE 3M Innovative Properties Company (US) 2003-04-02 EP claimed
US-20030045543-A1 Systems and methods for treating a mucosal surface 3M INNOVATIVE PROPERTIES COMPANY 2003-03-06 US claimed
WO-2002102377-A1 IMMUNE RESPONSE MODIFIERS FOR THE TREATMENT OF PERIODONTAL DISEASE 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-12-27 WO claimed
US-20020058674-A1 Systems and methods for treating a mucosal surface 3M INNOVATIVE PROPERTIES COMPANY 2002-05-16 US claimed
US-20020016332-A1 Imidazo-, oxazolo- and thiazolo- pyridineamines and naphthyridineamines which may be fused to cycloalkyl or benzene rings as immune reponse modifiers 3M INNOVATIVE PROPERTIES COMPANY 2002-02-07 US claimed
WO-2001097795-A2 SYSTEMS AND METHODS FOR TREATING A MUCOSAL SURFACE 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-12-27 WO claimed
WO-2001074343-A2 METHOD FOR THE TREATMENT OF DERMAL LESIONS CAUSED BY ENVENOMATION 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-10-11 WO claimed
US-4256819-A MEROCYANINES EASTMAN KODAK COMPANY (US) 1981-03-17 US claimed
US-4254198-A Electrophotosensitive materials for migration imaging processes EASTMAN KODAK COMPANY (US) 1981-03-03 US claimed
US-4166740-A CYANINE DYES EASTMAN KODAK COMPANY (US) 1979-09-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034237-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME CSGALNACT1, SLC43A1, OSTC LMNA 1233/4885CCR1 115/4885CCR5 1573/4885
US-20020058674-A1 Systems and methods for treating a mucosal surface INMT, ICOS, HRH2 LMNA 3662/4885CCR1 641/4885CCR5 1009/4885
US-20030045543-A1 Systems and methods for treating a mucosal surface INMT, ICOS, HRH2 LMNA 3662/4885CCR1 641/4885CCR5 1009/4885
US-20250115680-A1 PTK7 BINDING AGENTS, CONJUGATES THEREOF AND METHODS OF USING THE SAME PTK2B, PTK2, LTK LMNA 4448/4885CCR1 1607/4885CCR5 1523/4885
US-20020016332-A1 Imidazo-, oxazolo- and thiazolo- pyridineamines and naphthyridineamines which may be fused to cycloalkyl or benzene rings as immune reponse modifiers STING1, HRH4, ICOS LMNA 2041/4885CCR1 345/4885CCR5 224/4885
US-20260034238-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME MGAT3, GALE, GPI LMNA 775/4885CCR1 821/4885CCR5 2730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.