Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | USP1 | O94782 | 17/20 | 0.34 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27031470 | 1.00 | CSF1R (0.38) | CSF1RPDE2AUSP1WDR48 | |
| SCHEMBL29878992 | 0.92 | USP1 (0.39) | CSF1RPDE2AUSP1 | |
| SCHEMBL27031623 | 0.92 | USP1 (0.39) | CSF1RPDE2AUSP1 | |
| SCHEMBL27031506 | 0.90 | CSF1R (0.36) | CSF1RPDE2AUSP1 | |
| SCHEMBL29878443 | 0.90 | CSF1R (0.36) | CSF1RPDE2AUSP1 | |
| SCHEMBL27097114 | 0.88 | USP1 (0.37) | CSF1RPDE2AUSP1 | |
| SCHEMBL18865875 | 0.86 | USP1 (0.42) | PDE2AUSP1 | |
| SCHEMBL27031674 | 0.83 | USP1 (0.38) | PDE2AUSP1 | |
| SCHEMBL29878980 | 0.83 | USP1 (0.38) | PDE2AUSP1 | |
| SCHEMBL25430986 | 0.81 | USP1 (0.38) | PDE2AUSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308566-A1 | PURINE DERIVATIVES AS ANTICANCER AGENTS | Tango Therapeutics, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117425656-A | Purine derivatives as anticancer agents | 探戈医药股份有限公司 | 2024-01-19 | — | — | CN | disclosed |
| WO-2022197892-A1 | PURINE DERIVATIVES AS ANTICANCER AGENTS | TANGO THERAPEUTICS, INC. (US) | 2022-09-22 | — | — | WO | disclosed |