Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 18/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.70 |
| ▸ | TPO | P07202 | 16/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Verdiperstat SCHEMBL1536607 | 0.82 | MPO (1.00) | MPOOPRM1TPOKCNH2CYP3A4 | |
| Verdiperstat SCHEMBL23225670 | 0.72 | MPO (0.58) | MPOOPRM1TPO | |
| SCHEMBL27148100 | 0.66 | OPRM1 (0.51) | MPOOPRM1 | |
| SCHEMBL23225621 | 0.65 | MPO (0.55) | MPOOPRM1TPO | |
| SCHEMBL23218012 | 0.65 | MPO (0.55) | MPOOPRM1TPO | |
| SCHEMBL23217928 | 0.65 | OPRM1 (0.47) | MPOOPRM1 | |
| SCHEMBL27103046 | 0.65 | MPO (0.54) | MPOOPRM1TPO | |
| SCHEMBL23225647 | 0.64 | OPRM1 (0.46) | MPOOPRM1 | |
| SCHEMBL23218008 | 0.64 | OPRM1 (0.46) | MPOOPRM1 | |
| SCHEMBL1536784 | 0.64 | MPO (0.66) | MPOOPRM1TPOKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115103676-A | Combination therapy using pridopidine and another activator for treating amyotrophic lateral | 普瑞尼亚神经治疗有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-114945573-A | Prodrugs of myeloperoxidase inhibitors | 拜奥海芬治疗学有限公司 | 2022-08-26 | — | — | CN | disclosed |