Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | SORD | Q00796 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24738820 | 1.00 | CCR1 (0.39) | CCR1SORDRECQL | |
| SCHEMBL9070196 | 0.80 | CYP1A2 (0.33) | SORD | |
| SCHEMBL18061179 | 0.80 | — | — | |
| SCHEMBL20381536 | 0.76 | GAA (0.32) | — | |
| SCHEMBL23795894 | 0.74 | NPSR1 (0.37) | — | |
| SCHEMBL17898221 | 0.72 | KCNH2 (0.56) | — | |
| SCHEMBL4263702 | 0.70 | SORD (0.52) | CCR1SORDRECQL | |
| SCHEMBL872419 | 0.70 | HDAC8 (0.33) | — | |
| SCHEMBL3606048 | 0.70 | — | — | |
| SCHEMBL15577831 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308230-A1 | HETEROARYL INHIBITORS OF PLASMA KALLIKREIN | Takeda Pharmaceutical Company Limited (JP) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022197758-A1 | HETEROARYL INHIBITORS OF PLASMA KALLIKREIN | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2022-09-22 | — | — | WO | disclosed |