Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | GABRP | O00591 | 2/20 | 0.70 |
| ▸ | GABRD | O14764 | 2/20 | 0.70 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.70 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.70 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.70 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.70 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.70 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.70 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.70 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.70 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.70 |
| ▸ | GABRE | P78334 | 2/20 | 0.70 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.70 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.70 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.70 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2984227 | 0.94 | SMN1; SMN2 (0.66) | CYP1A2CYP2C19CYP2D6CYP2C9GABRP | |
| SCHEMBL2982587 | 0.92 | CYP1A2 (0.64) | CYP1A2CYP2C19CYP2D6CYP2C9GABRP | |
| SCHEMBL12204388 | 0.90 | CYP2D6 (0.62) | CYP1A2CYP2C19CYP2D6CYP2C9GABRP | |
| SCHEMBL15310716 | 0.90 | SMN1; SMN2 (0.63) | CYP1A2CYP2C19CYP2D6CYP2C9GABRP | |
| SCHEMBL2984890 | 0.90 | CYP1A2 (0.59) | CYP1A2CYP2C19CYP2D6CYP2C9GABRP | |
| SCHEMBL2985990 | 0.88 | KMT2A (0.66) | CYP1A2CYP2C19CYP2D6CYP2C9GABRP | |
| SCHEMBL13240117 | 0.87 | SMN1; SMN2 (0.57) | CYP1A2CYP2C19CYP2D6CYP2C9GABRP | |
| SCHEMBL15314664 | 0.86 | SMN1; SMN2 (0.56) | CYP1A2CYP2C19CYP2D6CYP2C9GABRP | |
| SCHEMBL2992771 | 0.86 | CACNA1G (0.62) | CYP1A2CYP2C19CYP2D6CYP2C9GABRP | |
| SCHEMBL14564120 | 0.85 | POLB (0.56) | CYP1A2CYP2C19CYP2D6CYP2C9GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142506-B1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2013-10-16 | — | — | EP | claimed |
| US-8394954-B2 | Benzophenone hybrids as anticancer agents and processes for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-12 | — | — | US | claimed |
| EP-2142506-B1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2013-10-16 | — | — | EP | disclosed |
| EP-2142506-B1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2013-10-16 | — | — | EP | disclosed |
| US-8394954-B2 | Benzophenone hybrids as anticancer agents and processes for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-12 | — | — | US | disclosed |
| US-8394954-B2 | Benzophenone hybrids as anticancer agents and processes for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-12 | — | — | US | disclosed |
| US-8394954-B2 | Benzophenone hybrids as anticancer agents and processes for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-12 | — | — | US | disclosed |
| US-20100174074-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-07-08 | — | — | US | disclosed |
| US-20100174074-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-07-08 | — | — | US | disclosed |
| US-20100174074-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-07-08 | — | — | US | disclosed |
| EP-2142506-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | Council of Scientific&Industrial Research (IN) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008120235-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008120235-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174074-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | TP53, RB1, MCL1 | CYP1A2 579/4885CYP2C19 495/4885CYP2D6 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.