Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | TSHR | P16473 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | GABRP | O00591 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2987985 | 0.86 | CYP1A2 (0.71) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL24495649 | 0.85 | ALDH1A1 (0.67) | CACNA1GALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2984227 | 0.81 | SMN1; SMN2 (0.66) | CACNA1GALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2984890 | 0.81 | CYP1A2 (0.59) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| SCHEMBL13240117 | 0.81 | SMN1; SMN2 (0.57) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12204388 | 0.80 | CYP2D6 (0.62) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL2985990 | 0.80 | KMT2A (0.66) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| SCHEMBL2982587 | 0.80 | CYP1A2 (0.64) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL15310716 | 0.79 | SMN1; SMN2 (0.63) | CACNA1GALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL14564120 | 0.79 | POLB (0.56) | ALDH1A1TSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142506-B1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2013-10-16 | — | — | EP | claimed |
| EP-2142506-B1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2013-10-16 | — | — | EP | disclosed |
| EP-2142506-B1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2013-10-16 | — | — | EP | disclosed |
| US-8394954-B2 | Benzophenone hybrids as anticancer agents and processes for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-12 | — | — | US | disclosed |
| US-8394954-B2 | Benzophenone hybrids as anticancer agents and processes for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-12 | — | — | US | disclosed |
| US-8394954-B2 | Benzophenone hybrids as anticancer agents and processes for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-12 | — | — | US | disclosed |
| US-20100174074-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-07-08 | — | — | US | disclosed |
| US-20100174074-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-07-08 | — | — | US | disclosed |
| US-20100174074-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-07-08 | — | — | US | disclosed |
| WO-2008120235-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174074-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | TP53, RB1, MCL1 | CACNA1G 4749/4885ALDH1A1 987/4885TSHR 4527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.