Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GRM7 | Q14831 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31633646 | 0.95 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL14562904 | 0.86 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL298783 | 0.86 | MAPT (0.57) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL14562854 | 0.85 | ALDH1A1 (0.43) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL14563011 | 0.85 | ALDH1A1 (0.48) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL13076895 | 0.83 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL298774 | 0.82 | ALDH1A1 (0.46) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL6743068 | 0.81 | HDAC1 (0.37) | MAPTKMT2A | |
| SCHEMBL31633659 | 0.81 | MAPT (0.59) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL14562831 | 0.80 | ALDH1A1 (0.50) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455399-B2 | N-(4-perfluoroalkyl-phenyl)-4-triazolyl-benzamides as insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-04 | — | — | US | claimed |
| US-20130023571-A1 | N- ( 4-PERFLUOROALKYL-PHENYL) -4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-01-24 | — | — | US | claimed |
| EP-2427439-B1 | N-(4-PERFLUOROALKYL-PHENYL)-4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-16 | — | — | EP | claimed |
| US-8455399-B2 | N-(4-perfluoroalkyl-phenyl)-4-triazolyl-benzamides as insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455399-B2 | N-(4-perfluoroalkyl-phenyl)-4-triazolyl-benzamides as insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455399-B2 | N-(4-perfluoroalkyl-phenyl)-4-triazolyl-benzamides as insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-20130023571-A1 | N- ( 4-PERFLUOROALKYL-PHENYL) -4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-01-24 | — | — | US | disclosed |
| US-20130023571-A1 | N- ( 4-PERFLUOROALKYL-PHENYL) -4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-01-24 | — | — | US | disclosed |
| US-20130023571-A1 | N- ( 4-PERFLUOROALKYL-PHENYL) -4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-01-24 | — | — | US | disclosed |
| EP-2427439-B1 | N-(4-PERFLUOROALKYL-PHENYL)-4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-16 | — | — | EP | disclosed |
| EP-2427439-B1 | N-(4-PERFLUOROALKYL-PHENYL)-4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-16 | — | — | EP | disclosed |
| EP-2427439-A1 | N- ( 4-PERFLUOROALKYL-PHENYL) -4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES | Syngenta Participations AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010127927-A1 | N- ( 4-PERFLUOROALKYL-PHENYL) -4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010127927-A1 | N- ( 4-PERFLUOROALKYL-PHENYL) -4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023571-A1 | N- ( 4-PERFLUOROALKYL-PHENYL) -4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES | PFAS, AADAC, FABP5 | CYP1A2 174/4885CYP2C9 118/4885CYP2C19 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.