Phosphoric Acid

Phosphoric Acid

SCHEMBL21596650

O=C1Oc2ccccc2C1c1ccccc1.O=P(O)(O)O.O=P(O)(O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.56
CYP2C9 P11712 3/20 0.46
ATM Q13315 2/20 0.42
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
MAPT P10636 3/20 0.38
LMNA P02545 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP3A4 P08684 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL501810 0.91 GAA (0.65) GAACYP2C9ATMMAOAMAOB
Pyrophosphoric Acid SCHEMBL31022403 0.91 GAA (0.51) GAACYP2C9ATMMAOAMAOB
Pyrophosphoric Acid SCHEMBL21596651 0.91 GAA (0.51) GAACYP2C9ATMMAOAMAOB
Phosphine SCHEMBL23295992 0.90 GAA (0.63) GAACYP2C9ATMMAOAMAOB
Acetamide SCHEMBL10703945 0.85 GAA (0.59) GAACYP2C9ATMMAOAMAOB
SCHEMBL30595412 0.84 GAA (0.54) GAACYP2C9ATMMAOAMAOB
SCHEMBL29880960 0.81 GAA (0.50) GAACYP2C9ATMMAOAMAOB
SCHEMBL8100817 0.81 GAA (0.50) GAACYP2C9ATMMAOAMAOB
Nonane SCHEMBL27663344 0.80 GAA (0.56) GAACYP2C9MAPTMEN1KMT2A
SCHEMBL20631015 0.78 GAA (0.67) GAACYP2C9ATMMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3810621-B1 3-PHENYL-BENZOFURAN-2-ONE DIPHOSPHATE DERIVATIVES AS STABILIZERS BASF SE (DE) 2024-08-07 EP disclosed
US-11767338-B2 3-phenyl-benzofuran-2-one diphosphate derivatives as stabilizers BASF SE (DE) 2023-09-26 US disclosed
US-11767338-B2 3-phenyl-benzofuran-2-one diphosphate derivatives as stabilizers BASF SE (DE) 2023-09-26 US disclosed
US-20210253617-A1 3-PHENYL-BENZOFURAN-2-ONE DIPHOSPHATE DERIVATIVES AS STABILIZERS BASF SCHWEIZ AG (CH) 2021-08-19 US disclosed
EP-3810621-A1 3-PHENYL-BENZOFURAN-2-ONE DIPHOSPHATE DERIVATIVES AS STABILIZERS BASF SE (DE) 2021-04-28 EP disclosed
CN-112292382-A 3-phenylbenzofuran-2-one diphosphate derivatives as stabilizers 巴斯夫欧洲公司 2021-01-29 CN disclosed
CN-112292382-A 3-phenylbenzofuran-2-one diphosphate derivatives as stabilizers 巴斯夫欧洲公司 2021-01-29 CN disclosed
WO-2019243267-A1 3-PHENYL-BENZOFURAN-2-ONE DIPHOSPHATE DERIVATIVES AS STABILIZERS BASF SE (DE) 2019-12-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210253617-A1 3-PHENYL-BENZOFURAN-2-ONE DIPHOSPHATE DERIVATIVES AS STABILIZERS DHPS, PIR, NQO1 GAA 1606/4885CYP2C9 167/4885ATM 1659/4885
US-11767338-B2 3-phenyl-benzofuran-2-one diphosphate derivatives as stabilizers DHPS, PIR, NQO1 GAA 1606/4885CYP2C9 167/4885ATM 1659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.