Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1248051 | 0.88 | IDO1 (0.57) | IDO1GAAL3MBTL1CHRM2CHRM4 | |
| SCHEMBL6650399 | 0.86 | GAA (0.55) | IDO1GAAL3MBTL1CHRM2CHRM4 | |
| SCHEMBL15873681 | 0.82 | GAA (0.50) | IDO1GAAL3MBTL1CHRM2CHRM4 | |
| SCHEMBL8674414 | 0.77 | IDO1 (0.52) | IDO1GAAL3MBTL1 | |
| SCHEMBL677532 | 0.77 | IDO1 (0.52) | IDO1GAAL3MBTL1 | |
| SCHEMBL10779906 | 0.74 | SIGMAR1 (0.48) | IDO1GAAL3MBTL1EPHX1MEN1 | |
| SCHEMBL14365763 | 0.74 | IDO1 (0.41) | IDO1GAAL3MBTL1CHRM2CHRM4 | |
| SCHEMBL29054020 | 0.72 | GAA (0.55) | IDO1GAAL3MBTL1CHRM2CHRM4 | |
| SCHEMBL27821886 | 0.72 | GAA (0.55) | IDO1GAAL3MBTL1CHRM2CHRM4 | |
| SCHEMBL4603729 | 0.72 | GAA (0.55) | IDO1GAAL3MBTL1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114958960-A | Drug screening method of targeted histone deacetylase SIRT6 regulator | 河南省人民医院 | 2022-08-30 | — | — | CN | disclosed |