SCHEMBL2988341

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2988339	1.00	CISD1 (0.36)	CISD1NPC1RAB9AKDM4EALDH1A1
	SCHEMBL2992895	0.91	NPC1 (0.39)	CISD1NPC1RAB9AKDM4EALDH1A1
	SCHEMBL2992893	0.91	NPC1 (0.39)	CISD1NPC1RAB9AKDM4EALDH1A1
	SCHEMBL2986112	0.91	DYRK3 (0.40)	CISD1NPC1RAB9AALDH1A1HPGD
	SCHEMBL2986120	0.91	DYRK3 (0.40)	CISD1NPC1RAB9AALDH1A1HPGD
	SCHEMBL4949454	0.90	CISD1 (0.40)	CISD1NPC1RAB9AKDM4EALDH1A1
	SCHEMBL2990900	0.84	ALOX5 (0.44)	CISD1NPC1RAB9AKDM4EALDH1A1
	SCHEMBL2990895	0.84	ALOX5 (0.44)	CISD1NPC1RAB9AKDM4EALDH1A1
	SCHEMBL2994951	0.84	KMT2A (0.41)	CISD1NPC1RAB9AKDM4EALDH1A1
	SCHEMBL2994948	0.84	KMT2A (0.41)	CISD1NPC1RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.