Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146159 | 0.87 | CASP6 (0.60) | CASP6TSHRLMNAALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL10571715 | 0.85 | CASP6 (0.58) | CASP6TSHRLMNAALDH1A1MEN1 | |
| SCHEMBL10756347 | 0.82 | CASP6 (0.55) | CASP6TSHRLMNAALDH1A1MEN1 | |
| SCHEMBL29111608 | 0.82 | CASP6 (0.55) | CASP6TSHRLMNAALDH1A1MEN1 | |
| SCHEMBL30629252 | 0.82 | CASP6 (0.55) | CASP6TSHRLMNAALDH1A1MEN1 | |
| SCHEMBL8841185 | 0.81 | CASP6 (0.62) | CASP6TSHRLMNAALDH1A1MEN1 | |
| SCHEMBL15408520 | 0.81 | VCAM1 (0.49) | LMNAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9706244 | 0.81 | TTR (0.62) | CASP6TSHRLMNAALDH1A1TPMT | |
| SCHEMBL2895332 | 0.81 | CASP6 (0.53) | CASP6TSHRLMNAALDH1A1TPMT | |
| SCHEMBL22121032 | 0.81 | TPMT (0.59) | CASP6TSHRLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022138791-A1 | EP2 ANTAGONIST | 小野薬品工業株式会社 | 2022-06-30 | — | — | WO | disclosed |