Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | KDR | P35968 | 9/20 | 0.68 |
| ▸ | PRKCZ | Q05513 | 7/20 | 0.68 |
| ▸ | CDK4 | P11802 | 5/20 | 0.68 |
| ▸ | CDK2 | P24941 | 5/20 | 0.68 |
| ▸ | RET | P07949 | 4/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.68 |
| ▸ | CCND1 | P24385 | 4/20 | 0.68 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.68 |
| ▸ | FLT3 | P36888 | 4/20 | 0.68 |
| ▸ | BTK | Q06187 | 4/20 | 0.68 |
| ▸ | MAP3K5 | Q99683 | 4/20 | 0.68 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.68 |
| ▸ | JAK2 | O60674 | 3/20 | 0.68 |
| ▸ | ABL1 | P00519 | 3/20 | 0.68 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.68 |
| ▸ | LCK | P06239 | 3/20 | 0.68 |
| ▸ | LYN | P07948 | 3/20 | 0.68 |
| ▸ | KIT | P10721 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10026708 | 1.00 | MAPT (1.00) | MAPTALDH1A1KDRPRKCZCDK4 | |
| SCHEMBL12259742 | 0.82 | ALDH1A1 (0.69) | MAPTALDH1A1KDRPRKCZRET | |
| SCHEMBL14498904 | 0.81 | PRKCQ (0.70) | MAPTALDH1A1KDRPRKCZCDK4 | |
| SCHEMBL16440374 | 0.81 | PRKCQ (0.70) | MAPTALDH1A1KDRPRKCZCDK4 | |
| SCHEMBL24606232 | 0.81 | PRKCZ (1.00) | MAPTALDH1A1KDRPRKCZCDK4 | |
| SCHEMBL18808417 | 0.81 | PRKCZ (1.00) | MAPTALDH1A1KDRPRKCZCDK4 | |
| SCHEMBL14845612 | 0.81 | PRKCZ (1.00) | MAPTALDH1A1KDRPRKCZCDK4 | |
| SCHEMBL20333841 | 0.81 | PRKCZ (1.00) | MAPTALDH1A1KDRPRKCZCDK4 | |
| Staurosporine SCHEMBL23793206 | 0.79 | PRKCQ (1.00) | MAPTALDH1A1KDRPRKCZCDK4 | |
| Staurosporine SCHEMBL23768489 | 0.79 | PRKCQ (1.00) | MAPTALDH1A1KDRPRKCZCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250025473-A1 | CELL IMPERMEABLE KINASE INHIBITORS TO TREAT SARS-COV-2 AND/OR HSV VIRAL INFECTIONS | ALBERT EINSTEIN COLLEGE MEDICINE (US) | 2025-01-23 | — | — | US | disclosed |
| CN-114958764-A | CD20 therapy, CD22 therapy, and combination therapy with CD19 Chimeric Antigen Receptor (CAR) -expressing cells | 诺华股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250025473-A1 | CELL IMPERMEABLE KINASE INHIBITORS TO TREAT SARS-COV-2 AND/OR HSV VIRAL INFECTIONS | PDPK1, DAPK1, DAPK2 | MAPT 900/4885ALDH1A1 4605/4885KDR 825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.