Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | GPR139 | Q6DWJ6 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | USP5 | P45974 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11881871 | 0.87 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19GPR139 | |
| SCHEMBL25837699 | 0.87 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19GPR139 | |
| SCHEMBL13831514 | 0.81 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19GPR139 | |
| SCHEMBL2069140 | 0.80 | HSD17B10 (0.50) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19POLB | |
| SCHEMBL874198 | 0.75 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19GPR139 | |
| SCHEMBL10919575 | 0.75 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19GPR139 | |
| SCHEMBL1562499 | 0.72 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19GPR139 | |
| SCHEMBL24233086 | 0.70 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19GPR139 | |
| SCHEMBL2996057 | 0.70 | MEN1 (0.63) | ALDH1A1SMN1; SMN2GPR139NPC1RAB9A | |
| SCHEMBL18493192 | 0.70 | HPSE (0.50) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | SIGA TECHNOLOGIES, INC. | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | EIF2AK2, HAVCR2, SNRPE | ALDH1A1 2072/4885SMN1; SMN2 509/4885CYP1A2 3195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.